1 It is a second generation tetracycline antibiotic that is active against gram-negative and gram-positive
Structure, properties, spectra, suppliers and links for: Minocycline (Tautomer), 10118-90-8
Introduction Minocycline is a highly lipophilic molecule, second-generation and semisynthetic tetracycline analogue [1]
Kemal Ugur Tufekci, Kursad Genc, in Advances in Protein Chemistry and Structural Biology, 2012 7
It is a second-generation tetracycline first synthesized in 1967 and commercialized in 1972
Minocycline is also available in extended release formulations for daily dosing and as a solution or powder for intravenous
Description
3
[3] Common side effects include vomiting, diarrhea, rash, and loss of appetite
Chemical structure of minocycline and its parent, tetracycline
Minocycline Hydrochloride is the hydrochloride salt of minocycline, a broad spectrum long-acting derivative of the antibiotic tetracycline, with antibacterial and anti-inflammatory activities
2 of 2
5,in a solution containing the equivalent of 10mg of minocycline per mL
Many of the derivatives exhibit potent, broad spectrum antibacterial activity against both tetracycline susceptible and resistant organisms
2 Identity
3 Source Category
- 4 of 4 defined stereocentres
It was developed in response to the growing rate of antibiotic resistant bacteria such as Staphylococcus aureus, Acinetobacter baumannii, and E
C23H30N4O17S2
07) Parent Compound
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Chemical Properties Physical Appearance Chemical structure of minocycline hydrochloride (MH)